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Title: Chitosan-based copaiba oil carrier polymeric systems: obtaining, characterization and antifungal activity in vitro
Authors: Bezerra, Gabriela Suassuna
Keywords: Copaiba oil;Microemulsioned system;Chitosan
Issue Date: 10-Jul-2020
Publisher: Universidade Federal do Rio Grande do Norte
Citation: BEZERRA, Gabriela Suassuna. Chitosan-based copaiba oil carrier polymeric systems: obtaining, characterization and antifungal activity in vitro. 2020. 24 f. Trabalho de Conclusão de Curso (Graduação em Farmácia) - Departamento de Farmácia, Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2020.
Portuguese Abstract: Copaifera multijuga Hayne is a typical Brazilian species known for producing copaíba oil-resin and its wide use by popular medicine due to its various pharmacological properties, however, its lipophilic character makes its use in new pharmaceutical systems difficult. Chitosan is a polymer of great interest in the pharmaceutical area due to its biocompatibility, filmogenic and bioadhesive properties, which allows its use by topic. To obtain chitosan polymeric systems with copaiba oil, two methods of obtaining films were used, the direct incorporation of the oil in the polymeric matrix and a microemulsioned carrier system. The interactions between the oil and the polymeric network were analyzed by infrared spectroscopy, thermogravimetry and X-ray diffraction techniques, as well as the characterization of the microemulsioned system used. The microemulsion obtained was effective in the formation of a copaiba oil carrier film, causing changes in the physical-chemical pattern that prove an adequate incorporation and increase in the diffusion of the oil in the culture medium, and may become a therapeutic alternative for skin injury treatments, since growth inhibition halos were observed in strains of Candida spp.
Other Identifiers: 2016086000
Appears in Collections:Farmácia

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